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[4-(6-chloro-naphthalene-2-sulfonyl)-piperazin-1-yl]-(3,4,5,6-tetrahydro-2h-[1,4']bipyridinyl-4-yl)-methanone

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the class of organic compounds known as 2-naphthalene sulfonic acids and derivatives. It is also referred to by the code name ZEN. The molecule has been studied primarily as an experimental inhibitor of serine proteases and has been co-crystallized in complex with trypsin and factor Xa in structural biology studies. There are no approved clinical indications or marketed products containing this compound. Its primary use appears to be as a research tool for studying protease inhibition mechanisms[1][3][7].

Other names
1-(6-chloronaphthalene-2-sulfonyl)-4-{[1-(pyridin-4-yl)piperidin-4-yl]carbonyl}piperazine1-[(6-chloronaphthalen-2-yl)sulfonyl]-4-[1-(pyridin-4-yl)piperidine-4-carbonyl]piperazine[4-(6-Chloro-Naphthalene–2-Sulfonyl)–Piperazin–1–Yl]–(3,4,5,6-Tetrahydro–2h-[1,4′]Bipyridinyl–4-Yl)–Methanone
02

Targets

F10 (Factor Xa)

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